"The reason I don't use D and A dust everytime is to give them a chance to process what is already in their system. They get both two out of every three feedings. Herptivite has beta-carotene (which they maybe can use to turn into A) and no D either as that is in their calcium powder. Both A and D can build up to toxic levels so a little break is good.
Here's the long version as explained by Ed.
"mixed, the fat soluable vitamins will catalyze a more rapid oxidation of each other (which is why Rep-Cal and Herptevite are seperate with one haveing A and E and the other D3) than if they are kept seperate (however they still will oxidize which is why the recommendation is to replace the supplements every six months or so).
However in the digestive tract, A, D3 and E compete for uptake by the animal. This is why the ratio of the vitamins in the supplement should be somewhere close to 10 to 1 to 0.1 (A to D3 to E) as large variations outside of this range can cause deficiencies of one or more of the vitamins (this was (may still be) the most common cause of "MBD" (metabolic bone disease which is actually a group of diseases that present the same symptoms by disrupting calcium metabolism) when the diet contained excessive vitamin A). I have a whopping headache so I am not going to check the labels but you need to make sure that if you are mixing the two before dusting that the resulting ratio of A3 and E are correct which may cause you to change the amount you mix. By alternating the dustings with the feedings, there is less issue with uptake of the fat soluable vitamins as the frog can store the excess in the fat, liver and skin (depending on the vitamin)..
This also allows for alternation of calcium supplementation as excessive calcium can also cause conditional deficiencies and in extreme excess and a high fat diet cause the deposition of calcium salts in the digestive tract. "