One pupil open and the other one closed is called "Anisocorie" in french (I don't know the word in english).
This is related to a neurological problem for humans.
For reptile and amphibians they have this propertie which is not pathological (Completely normal), except if it is all the time.
This should occur when one eye is shine by the light (The right eye of your frog on the picture) and the other one has no light on it (Left eye on the picture).


			


					
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