I rarely feed them mice and I've got a 7-8 inch male. That should answer the question. Number 1 food for Pyxies, in my opinion, is/are nightcrawlers. Mice are fine every now and then but why feed a live one? The frozen ones you can buy are perfectly fine and they were killed "humanely" as opposed to letting them be bitten, crushed and suffocated to death by a huge frog.