Just to give it a post-bump forward for those questioning neosporin...

Original neosporin or bacitracin are safe to use, but may or may not treat some amphibian issues. It would depend on the infectious bacteria and how severe the infection. Any severe infections and/or infections with subsequent lethargy or weakness, lack of eating, diarrhea, bloating may have sepsis and would need systemic antibiotics by a vet.

Keep in mind, there are also fungal and parasitical infections that could be contributing.

Hope this helps.