Hi! Unfortunately, I think you are going to need to take her to an exotic vet to get a definitive diagnosis. It is not impossible for frogs to develop cancer but it is very rare and unlikely. Scientists have been researching frogs and the fact that they rarely develop cancer and are looking into the genetics of amphibians for any correlations and whether they may hold a key to fighting cancer in humans. Cancer usually grows very rapidly and a cancerous growth typically becomes very hard, like a stone. If your girl's lump hasn't grown fast and/or feels soft, then it's most likely a lipoma, or fatty tumor. Given that she is active and has a good appetite, I don't believe it's anything to worry about. However, if any changes in appearance, size, appetite/behavior occur... then I would most definitely take her to a vet. I wouldn't treat her with any more medication because that may actually cause a problem. Although I am not a professional, I've had my share of dealing with cancer in different animals and from what I have been told and researched... cancer acts the same way in all species, and this doesn't "appear" to cancer, but like I said... you'd need a vet to definitively diagnose or rule it out. I will do some more research specifically on frogs and will let you know if I find anything more. You specifically said that you only recently came to discover that it may be something to be concerned about... Can you explain what led you to that discovery/concern or give me some additional info? Thanks!