1cc is a lot for a small toad. Generally i only give a few drops at a time of reptaboost to our toad. Hope Hopper improves soon. Would make sure she gets to rest too. How warm is their tank? Vet insusted we keep Mr Toad at 80 degrees when he was really ill with MBD ( now we make sure he is at least 75). Hibernation or brumation seems hard on amphibians. Hope Hopper is ok. Mr Toad occasionally ends up on his back while he is moving around a lot because the MBD left him with limb difficulties. I hope Hopper doesnt go upside down again. After i found Mr Toad dried out and seemingly dead, i soaked him but too long at first and he had edema. Soaking all day is too long possibly for a debilitated toad...we had to soak Mr Toad for just brief periods after that (vet said no more than 20 minutes at first a few times per day until he peed out the extra fluid). Hope Hopper improves soon with rest and TLC. Would let her rest after the reptile feeding and see if she will defecate after a very brief soak later. How is she moving around? Any TLC like feedings, soaks etc need to be gradual so she can rest and get her energy back. You mentioned that the soak had calcium in it. Is it possible she may be going through MBD again? Mr Toad needed weeks of calcium gluconate 1 drop 2x per day to really improve after i found him stiff. Do the toads get regular calcium and D3! and vitamins and mineral dustings ( alternate days)?