Hi! I think I can help a bit. One thing to keep in mind is heat. If it gets too hot running out of water increases in likelyhood. You frog will likely be fine for a couple days as long as the caretaker you have lined up makes sure to get the water dish nice and full. Also leave instructions to make sure to remove all substrate(coco fiber or dirt, doesn't matter.) that the frogs have tracked in. A bottom layer of substrate in the dish will absorb water and make it run out faster. Another thing is how late you will arrive Wednesday. Early and they've been alone 2 days. If you're coming home in the evening it's effectively 3 days. I've left my Pacific Treefrogs alone for a couple days before, and they're still here and just fine. I've done this twice, maybe three times. Each time upon my return the dish is almost empty or fully empty and they were sitting in it trying to soak up the last of the moisture. My own home, however has no temperature regulation, and is typically the same temp as it is outside. If you can make sure its not too hot in your house, they'll probably do even better. I hope this sets your mind at ease a bit. Good luck finding someone!