Hello, I'm so sorry to hear he still hasn't gotten any better. I Have been following this from the start and IMO I think yes it may be that time. If the meds and everything hasn't even perked him up abit he just may not have any fight left in him, not being able to even open his eyes is a clear sign IMO that he may just want to go to froggy heaven. If you cant get him to eat a cricket I don't think he will be able to eat a pink mouse. This is just my opinion though from what I have read and I'm by far no vet. I know its hard ( I have been there before) but it may be the best thing for the frog. And please don't let this discourage you from getting another, it could of started at the pet shop and it was just one of those cases were it progressed very fast. Alot of these stores don't put vitamins on there feeders before feeding. And most the time they get them as babies when these vitamins are a crucial part of there diet for proper growth and development.