At first I looked at the squid/mussel idea and thought that it was a pretty neat idea for a winter based diet if all else fails; where I live I actually only have one place to really buy Nightcrawlers now that the closest Walmart only orders Crawlers once a month. I find that crickets are too much of a nuisance to keep and roaches are a no-go on my mother's wishes. $5 USD for 14 or so worms wasn't bad compared to $6 for 12 at the LFS that I have to go to.
Though with captive bred/domestic animals, it could be arguable that this sort of diet would be perfectly fine - I only imagine that you would need to thoroughly wash the squid/mussels prior to feeding. I understand that owning pets like this require you to "simulate" the wild in their habitat but out in the wild they would not be tong/dish trained, nor would they always have the perfect environment.
To me this idea is like applying the frog sausage diet I've been researching using lean ground beef/chicken/liver. That idea alone is unnatural because frogs don't find sausages out in the wild with protein in them lol. If the seafood is edible for humans and comes from a trustworthy source, that would mean that preparing the food is where you eliminate the bacteria aspect in the idea of feeding it to a pacman frog. "Yeah but it's food for humans, not food for pacman frogs" : Understandable, but someone has to have gone through trial and error to come back and share with the rest of the group.