I believe I've solved this mystery...

The female's lips are almost completely normal now, but it doesn't seem to matter now unfortunately, given my last update to the other issue: http://www.frogforum.net/food-feeder...html#post47822

I'm pretty positive now that it was the chemicals on my floor... Why? The male jumped out of the tank and was on the floor for literally a couple of seconds. I washed him off as well as I could and put him back. Now his lip (still much larger on one side strangely) is completely swollen again. Dang it.