need to pick up your brains

so, giant vs dwarf, differences other then size/appearance/genetic code?
same husbandry, same geographic area more or less.
we all know that mixing frog species is no-no in captivity and that giants as well as dwarfs can be housed in groups, thus question, can those species be housed together in a big enough enclosure, provided frogs are big enough to not become food for each other ? what do you think? as well do you think or have any information if crossbreeding is possible given that they are so close genetically.