I had a Whites tree frog with the spots on his eye and my vet said it is from too much fat in his diet. Unfortunately this cannot be cured. Prevention by not over feeding our charges is the best way to make sure we don't see it. Domestically raised crickets apparently have a high fat content so too many crickets is not healthy. I had to put my frog on a diet or 2 crickets a week and an exercise plan. Such fun.