GE Silicone I and II, long used by fish- and frog-keepers and generally thought of to be aquarium safe, is probably no longer so. GE began using mildew inhibitors (Bioseal) recently in most their silicone products, even if the label says "100% silicone" and doesn't mention anything about mildew. According to an email from GE, all their silicone has trace amounts mildew inhibitors now except for the 1200.
The result? People are reporting massive fish and coral die-off. I'm sure frogs would be affected too, although perhaps not as much.
http://www.canreef.com/vbulletin/sho...light=Silicone
Silicone crash - Canreef Aquatics Bulletin Board
Still, there are some who insist the GE I and II that says 100% silicone with no indication of added mildew inhibitors is still safe to use. Judge for yourself.