Joe Pacman frogs are tempermental animals. most do not like being handled. Even as their care giver they see if they see you as a threat like if you show anger and frustration your frog will pick up on your emotions and become stressed. You must remain calm.
There is a sticky post at the top of this section of threads called "Trouble in the enclosure" please read that thread and answer the questions. This will assist us I. figuring out what may be wrong with your Pacman.