Diane,

I have a similar situation - our toad's first eye went cloudy, we tried gentamicin sulfate and maracyn 2 (minocycline) with no luck, not to mention the usual saline drops, etc. He seemed stable but now, 5 months' later, the good eye is now clouding over. The description of behaviour, etc. is identical to what I am experiencing. I combed through the local university's biology department, and the local zoo, looking for herpetologists. The curator at the local zoo emailed me a link to http://www.pollywogsworldof frogs.com/Text-html/frong-rx-fungal.html and under "cloudy eyes" it states that this is caused by a bacteria called chryseobacterium, and to treat it, you need to use methelene blue full strength as eyedrops, 2x/day for 3 days. Spray 5% solution of Baytril (bayer corporation liquid formulation, active ingredient is enrofloxacin) on the frog FIRST before using the methelene blue. The site claims your froggies will be fine in 3 days or so.

I just found this information, so I will be heading to my vet armed with this information on Monday. Meanwhile, quarantine the affected toads if you can. You can use Wiki and look up chryseobacterium, as well as a second possible aeromonas hydrophila, both are gram negative, rod shaped bacteria, I suspect both will respond to the use of a floxacin. WHile I am surprised that the gentamicin and minocycline were unsuccessful (both attack gram negative bacteria), I have read that chryseobacterium is resistant to many forms of antibiotics.

You need to go to the vet to get a prescription - you cannot by Baytril without one. If you need to, draw up a waiver and sign it, telling your vet you absolve him/her from responsibility should the toads get sick or die because of the treatment. From what I read, this bacterial infection is likely lethal in the long run. THe waiver is probably the only way a reluctant vet will help you out. I am a lawyer, make sure your waiver is clear that you will not sue the vet for whatever the outcome is.

Good luck. I will be back next week to report in.