Hi Mark, He is a big beautiful boy. Ive only come across a frog with an eye problem once. It actually had only one eye and the space where the other eye should have been was just the beautiful skin. It looked odd as there was no raised bump where the eye should have been. I wanted to buy it but I knew the store had a problem with red leg a while back and didn't want to risk it. It was managing just fine. Even though your frog has two eyes but has trouble opening one of them, this maybe just something that your frog might just have to live with. He's gorgeous and the eye thing makes him unique in my opinion. If you wanted to pursue it further you could see what you vet thinks.