I do handle my frogs from time to time for cage cleaning or photoshoots (I usually do both at the same time to get the most out of a handling). Hands are always well rinsed with plain water and I never do it on a day when I've touched any kinds of potentially nasty chemicals like hand sanitizers, sunscreen, paint, pumped gas, etc.
Gloves are a good option too like Martin suggests, and I keep some on hand in the event I have to move a frog and I don't know where my hands have been.
How long have you had them, were they adults when you acquired them? They are Hyla cinereas? I only have one experience with the one I own, and it took him a little over a year to reach full size, so that might help you narrow the age down. Or ask to see their drivers licence or birth certificate.





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