ive had firebelly toads my whole life. my first pet as a kid. I currently have the two right now. When i first got Urlacher about 6 months ago i used to mist him all the time. but he didnt seem like he liked it. than bout three months ago i got urlachers wife (havent named her yet kinda just stuck with urlachers wife) i dont mist them at all. and they live happily together. I change their water about every day or every other. depending on how dirty it is. They live fine. i liv in ct and right now its winter. my house stays pretty warm though. back in October we had bad snow storm and lost power for about three to four days. room temp dropped to about 60 degrees. all the pet supplies shops were closed for about a week! literally. so they didnt even get to eat. if your only leaving your frogs for 2 days i wouldnt worry about. spray before you leave and just spray when you get home.