Frogwarrior

​Does Inbreeding have any major effect on captive populations of Bufo Incilius Alvarius? Can sibling toads and/or frogs breed with one another? ie. Brother and sister? Mother and Son? NOT TO BE WEIRD! This is a serious question and maybe I'm just really ignorant on the subject but I want to know much more. Please anyone really knowledgeable on this subject HELP. Thank you.